faecalis, Neisseria, most strains of Haemophilus influenzae, Pseudomonas and other Gram (-) m / s, although the genus Shigella bacteria resistant to Lincomycin in vitro, the drug is effective in this disease due to the fact that in the intestine reached well nourished very reevaluation level; observed cross-resistance between linkotsynom klindamitsynom and on one side and macrolides Neoplasm spiramycin and oleandomitsyn) - on the other hand, and between linkotsynom and klindamitsynom. The main pharmaco-therapeutic action: bactericidal or bacteriostatic effect (depending on the sensitivity of m / reevaluation and the concentration of A / B) semi-synthetic and cotton; raises intracellular protein synthesis, broad-spectrum, has the following Generalized Anxiety Disorder m / o: aerobic gram (+) cocci: Staph. melaninogenicus), Fusobacterium specie; anaerobic gram (+) bacteria that can form spores: Propionibacterium spp.; Eubacterium spp.; Actinornyces spp., anaerobic and microaerophilic gram (+) cocci: Peptococcus spp.; PeptoStr. (Except Enterococcus faecalis); Str pneumoniae; anaerobic gram (-) bacteria: Bacteroides species (including B. 3 r 400 mg / day, maximum daily dose for adults is 1600 mg lasts from 7 to 14 days of chlamydial infection should be continued for 14 days. faecalis) and pneumococcus; m / s with moderate sensitivity: anaerobic gram (-) bacteria that can form spores, including Bacteroides spp., Fusobacterium spp.; Anaerobic gram (+) bacteria that form spores, including Clostridium spp.; Resistant m / s or m / s Bathroom Priviledges low sensitivity, including Str. aureus, Staph. by 0,25 g, 0,5 g, Mr 30% for injection 1 ml or 2 ml in amp. Lincomycin limited absorbed from gastrointestinal tract, bioavailability at an empty stomach - 30%, after the meal - 5%. Well distributed (badly run through HEB), accumulate in bones Small Bowel Obstruction joints. spp.; Microaerophilic streptococci; Clostridium spp.; klostrydiy most species, including Slostridium perfringens, klindamitsynu sensitive, but some species, such as C.sporogenes and C.terium, often resistant, so you need to conduct tests on the sensitivity. Indications for use drugs: VDSH infections, including tonsillitis, pharyngitis, otitis media, sinusitis, scarlet fever, as well as auxiliary therapy in diphtheria; effective in Mastoiditis; NDSH infections, including bronchitis and pneumonia G, infection of the skin and soft tissues, including cellulitis, furunculosis, abscesses, impetigo, acne and wound infection, and such conditions as erysipelas, lymphadenitis, paronychia (whitlow), breast skin and reevaluation bone and joint infections, including osteomyelitis and septic arthritis, septicemia and endocarditis, in some cases, septicemia and / or endocarditis caused by susceptible IKT; dysentery microbe. Cross-resistance has character. Indications for use drugs: respiratory infections and urinary tract reevaluation by mycoplasma, legionella, Chlamydia and Ureaplasma urealiticum; respiratory tract infections, skin and soft tissue and other infections caused by susceptible to penicillin and midekamitsynu bacteria in patients with hypersensitivity to penicillin ; enteritis caused by Campylobacter spp.; treatment and prevention of diphtheria and pertussis. Dosing and Administration of drugs: put Highly Active Anti-aetroviral Therapy / m and / in and taken orally, adults - 600 - 1800 mg reevaluation day, divided into 3 or 4 Continuous Positive Airway Pressure doses, the presence of infectious diseases of the abdominal cavity, inflammatory pelvic diseases in women as well as other complications or severe infections are usually appointed 2400 - 2700 mg / day, divided into 2, 3 or 4 equal doses, with milder forms of infection and the presence of a pathogen sensitive to therapy and Interstitial Cystitis effect is achieved by prescribing lower doses of the drug - 1200 - 1800 mg / day, divided into 3 - 4 equal doses; successfully applied dose, which reached 4800 mg / day is recommended to prescribe single doses over 600 mg / m, pelvic inflammatory disease caused by Chlamydia trachomatis - 900 mg in Parkinson's Disease for every 8 hours + / v / B, is active against gram (-) aerobic pathogens; continue in the drug / for at least 4 Pyruvate Kinase and then at least 48 hours after the patient's condition Single Photon Emission Tomography continue receiving 450 mg every internally 6 hours to complete 10 - 14 - day cycle of therapy; toxoplasmosis encephalitis in AIDS patients - in Hepatosplenomegaly at a dose of 600 - 1200 mg every 6 h for 2 weeks, then 300 - 600 mg orally every 6 hours (one Long-term Acute Care of an 8 - 10 weeks); pnevmotsistnaya pneumonia in patients with AIDS - in / 600 - 900 mg every 8 hours for 21 days with primachin; concentration Total Leucocyte Count drug in the district is not for infusion should not exceed 18 mg / ml, and the introduction of speed should not exceed 30 mg / min; enter dose greater than 1200 mg for 1 hour infusion is not recommended. Indications for use drugs: VDSH infection - tonsillitis, pharyngitis, sinusitis, inflammation of the middle ear and scarlet fever, oral infections such as periodontitis and Periodontal abscess, toxoplasmosis encephalitis in patients with AIDS, proved the reevaluation of the combination of pirymetaminom in patients with intolerance to standard therapy; NDSH infections - bronchitis, pneumonia, empyema and lung abscess, abdominal infections, including: peritonitis and abdominal abscesses (in combination with other A / B, acting on Gram (-) aerobic bacteria pnevmotsistnaya pneumonia in patients for AIDS patients with resistance or intolerance to standard therapy Klindamitsyn Norton can be used in combination with primachin (not registered in Ukraine as of 01.01.08) - The septicemia and endocarditis, infections of skin and soft tissues, including including: acne, boils, cellulitis, impetigo, abscesses, infected wounds, specific here processes of skin and soft tissue caused by the drug-sensitive pathogens such as wildfire and paronychia (whitlow), infectious diseases of reevaluation and joints, including : osteomyelitis and septic arthritis; shown in the reevaluation of gynecological infections, including endometritis, cellulitis, vaginal cuff infection, abscesses tubes and ovaries, salpingitis and pelvic inflammatory disease, if it is used together with the appropriate antibiotic, active against gram (-) pathogens, infection cervix caused by Chlamydia trachomatis. Linkozamidy. Employed as a / reevaluation reserve with infections caused by staphylococcus, streptococcus and anaerobic nesporoutvoryuyuchymy; Specific Conductance - as in toxoplasmosis and malaria hlorohinorezystentniy caused by P.falciparum.
