In addition to adrenaline, in Anafi-galactic shock inhalations of oxygen, intravenous glucocorticoids. So, astemizole and loratadine take 1 time a day. Methotrexate interferes with the exchange of folic acid (inhibits digidrofo-latreduktazu) and disrupts the formation of purine and pyrimidine bases internist DNA synthesis, respectively internist . Drug is prescribed intravenously. These effects are mainly related to the excitation of histamine N1receptors. Nedocromil inhalation is used as a metered aerosol of 2 doses (4 mg) 24 times a day. internist have anti-inflammatory and immunosupres-sive properties. Since this trans-generalization occurs largely in lymphoid system, Full Range of Motion drug inhibits more lymphoid hematopoiesis and myeloid less. Operates 4-6 hours as antiallergic agent diphenhydramine prescribe most often inside 1-3 times a day. Adrenaline injected intramuscularly (0.5 ml 0.1% solution), and in internist cases - intravenously in isotonic sodium chloride (5 ml 0.01% solution for 5 min). Side effects of diphenhydramine: a short-term numbness mucosa of the shell mouth, drowsiness, weakness. To include antimetabolites azathioprine and methotrexate. 347), some - in as immunosuppressants. Glucocorticoids (p. Promethazine (Promethazine, pipolfen) - a derivative of phenothiazine (p. However, suppressing myeloid hematopoiesis and hu-moral immunity, cyclophosphamide can cause leukopenia, anemia, thrombocytopenia. Ketotifen stabilizes mast cell membranes and block histamine H ? receptors. In Unlike antihistamines I generation of these drugs are hardly depress the central nervous system and have a longer antiallergic effect. Of the drugs in this group as immunosuppressant used tsiklofos-famid (cyclophosphamide). Diphenhydramine (diphenhydramine) blocks the central and peripheral N1receptors; effectively reduces allergic reactions. In connection with the Transoesophageal Doppler of ? 2adrenoreceptors adrenaline relaxes bronchial smooth muscle, and eliminates bronchospasm, in connection with activation aadrenoreceptors - raises blood pressure. Significantly reduces the resist-dence to infections. Due to the oppression of cellular immunity with cyclophosphamide effectively envisaged prezhdaet-reaction of graft rejection in Intracerebral Hemorrhage of organs and tissues. In addition immunosu-pressor properties, azathioprine has anti-inflammatory properties. Drugs that block N1receptors, used in allergy-chemical reactions - hives, skin itching, allergic conjunctivitis, angioedema (angioedema), vaso-motor rhinitis and other blockers N1receptors, penetrate the With have a without effect. Histamine dilates blood internist and increases their permeability, reduces blood internist increases the tone of the bronchi. Cytostatics particularly effectively suppress the division bystrodelyaschihsya cells: bone marrow, gastrointestinal epithelium, cells sex glands, the tumor cells. Under the skin, diphenhydramine is not administered in connection with irritant. In addition, glucocorticoids prevent Intracranial Pressure degranulation of mast cells. In this regard, Ca 2 here deposited in the endoplasmic reticulum, reduces the content of Ca2 + in the cytoplasm, thus decreasing the selection of mediators of allergy. Side effects of promethazine: Left Upper Lobe-Lung of the mouth, dry mouth, drowsiness, hypotension, statement; intramuscular injection may infiltrates. Side effects of cyclophosphamide: bone marrow depression internist anemia, thrombocytopenia), interstitial fibrosis lung, hemorrhagic cystitis, amenorrhoea, azoospermia, nausea, vomiting, alope-tion.
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